Dr. Proctor discusses examples of and reasons for hypodermic injection rather than oral administration of drugs, examines injection methods, and shows various styles and construction of syringes. He also gives a historical account of development of the hollow needle and intravenous injection by such scientists as Serturner, Pravaz, Wood, Osler, LaFarge, and Wren. Dr. Walter Dandy, professor of surgery at Johns Hopkins, shows the endemic method of applying a drug to the skin by blistering the skin. He also offers examples of and reasons for the need to administer drugs hypodermically rather than orally. Using an orange, a nurse demonstrates the method for teaching laymen how to administer an insulin injection.